OVERDOSE
Numerous reports of ingestion of large doses of estrogen-
containing oral contraceptives by young children indicate
that serious ill effects do not occur. Overdosage of estrogen
may cause nausea, and withdrawal bleeding may occur in
females.
There have been no reports of acute overdosage with the
androgens.
CONTRAINDICATIONS
Estrogens should not be used in women with any of the following
conditions:
- Known or suspected cancer of the breast except in
appropriately selected patients being treated for metastatic
disease.
- Known or suspected estrogen-dependent neoplasia.
- Known or suspected pregnancy (See Boxed Warning ).
- Undiagnosed abnormal genital bleeding.
- Active thrombophlebitis or thromboembolic disorders
- A past history of thrombophlebitis, thrombosis, or
thromboembolic disorders associated with previous estrogen
use (except when used in treatment of breast malignancy).
Methyltestosterone should not be used in:
- The presence of severe liver damage.
- Pregnancy and in breast-feeding mothers because of
the possibility of masculinization of the female fetus
or breast-fed infant.
|
|
