DESCRIPTION
ADRUCIL® Injection (fluorouracil injection, USP),
an antineoplastic antimetabolite, is a colorless to faint
yellow aqueous, sterile, nonpyrogenic injectable solution
for intravenous administration. Each 10 mL contains 500
mg of fluorouracil; pH is adjusted to 8.6 to 9.4 with
sodium hydroxide and hydrochloric acid if necessary.
Chemically, fluorouracil, a fluorinated pyrimidine, is 5-fluoro-2,4(1H,3H)-pyrimidinedione.
It is a white to practically white crystalline powder which
is sparingly soluble in water. It has molecular formula
C4H3FN2O2 with
a molecular weight of 130.08.
|
|
