DESCRIPTION
DOVONEX (calcipotriene ointment) contains the compound
calcipotriene, a synthetic vitamin D, derivative for topical
dermatological use.
Chemically, calcipotriene is (5Z,7E, 22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19),
22-tetraene-1 alpha, 3 beta, 24-triol-, with the empirical
formula C27H40O3, a molecular weight of 412.6.
Calcipotriene is a white or off-white crystalline substance.
DOVONEX contains calcipotriene 50 ug/g in an ointment
base of dibasic sodium phosphate, edetate disodium, mineral
oil, petrolatum, propylene glycol, tocopherol steareth-2
and water.
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