DESCRIPTION
DETROL Tablets contain tolterodine tartrate. The
active moiety, tolterodine, is a muscarinic receptor antagonist.
The chemical name of tolterodine tartrate is (R)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-
phenylpropanamine L-hydrogen tartrate. The empirical formula
of tolterodine tartrate is C26H37NO7,
and its molecular weight is 475.6.
Tolterodine tartrate is a white, crystalline powder. It
is soluble at 12 mg/mL in water at room temperature and
is soluble in methanol, slightly soluble in ethanol, and
practically insoluble in toluene. DETROL Tablets for oral
administration contain 1 or 2 mg of tolterodine tartrate.
The inactive ingredients are colloidal anhydrous silica,
calcium hydrogen phosphate dihydrate, cellulose microcrystalline,
hydroxypropyl methylcellulose, magnesium stearate, sodium
starch glycolate (pH 3.0 to 5.0), stearic acid, and titanium
dioxide.
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