DESCRIPTION
Cordran Tape (Flurandrenolide Tape, USP) is a transparent,
inconspicuous, plastic surgical tape, impervious to moisture.
It contains Cordran (Flurandrenolide, USP), a potent corticosteroid
for topical use. Flurandrenolide occurs as white to off-white,
fluffy crystalline powder and is odorless. Flurandrenolide
is practically insoluble in water and in ether. One g
dissolves in 72 mL of alcohol and in 10 mL of chloroform.
The molecular weight of flurandrenolide is 436.52.
The chemical name of flurandrenolide is Pregn-4-ene-3,20-dione,
6-fluoro-11,21 dihydroxy-16,17-[(l-methylethylidene) bis
(oxy)]-, (6a,
11b,
16a)its
empirical formula is C24H33FO6
.
Each square centimeter contains 4 mg
(0.00916 mmol)
flurandrenolide uniformly distributed in the adhesive
layer. The tape is made of a thin, matte-finish polyethylene
film that is slightly elastic and highly flexible.
The adhesive is a synthetic copolymer of acrylate ester
and acrylic acid that is free from substances of plant
origin. The pressure-sensitive adhesive surface is covered
with a protective paper liner to permit handling and trimming
before application.
|
|
