DESCRIPTION
Cordarone is a member of a new class of antiarrhythmic
drugs with predominantly Class III (Vaughan Williams’
classification) effects, available for oral administration
as pink, scored tablets containing 200 mg of amiodarone
hydrochloride. The inactive ingredients present are colloidal
silicon dioxide, lactose, magnesium stearate, povidone,
starch, and FD&C Red 40. Cordarone is a benzofuran
derivative: 2-butyl-3-benzofuranyl 4-[2-(diethylamino)-ethoxyl-3,5diiodophenyl
ketone hydrochloride. It is not chemically related to
any other available antiarrhythmic drug.
Amiodarone HCl is a white to cream-colored crystalline
powder. It is slightly soluble in water, soluble in alcohol,
and freely soluble in chloroform. It contains 37.3% iodine
by weight.
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