OVERDOSE
Serious ill effects have not been reported following acute
ingestion of large doses of estrogen-containing oral contraceptives
by young children. Overdosage of estrogen may cause nausea
and vomiting, and withdrawal bleeding may occur in females.
CONTRAINDICATIONS
Estrogens should not be used in individuals with any
of the following conditions:
1. Known or suspected pregnancy (see
BOXED WARNING). Estrogens may cause fetal harm when administered
to a pregnant woman.
2. Undiagnosed abnormal genital bleeding.
3. Known or suspected cancer of the
breast except in appropriately selected patients being
treated for metastatic disease.
4. Known or suspected estrogen-dependent
neoplasia.
5. Active thrombophlebitis or thromboembolic
disorders.
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