PATIENT INFORMATION

Physicians are advised to discuss the following issues with patients for whom they prescribe Celexa^TM.

Although in controlled studies Celexa^TM has not been shown to impair psychomotor performance, any psychoactive drug may impair judgment, thinking or motor skills, and so patients should be cautioned about operating hazardous machinery, including automobiles, until they are reasonably certain that Celexa^TM therapy does not affect their ability to engage in such activities.

Patients should be told that, although Celexa^TM has not been shown in experiments with normal subjects to increase the mental and motor skill impairments caused by alcohol, the concomitant use of Celexa^TM and alcohol in depressed patients is not advised.

Patients should be advised to inform their physician if they are taking, or plan to take, any prescription or over-the-counter drugs, as there is a potential for interactions.

Patients should be advised to notify their physician if they become pregnant or intend to become pregnant during therapy.

Patients should be advised to notify their physician if they are breast feeding an infant.

While patients may notice improvement with Celexa^TM therapy in 1 to 4 weeks, they should be advised to continue therapy as directed.