DESCRIPTION
ARIMIDEX® (anastrozole) tablets for oral administration
contain 1 mg of anastrozole, a non-steroidal aromatase inhibitor.
It is chemically described as 1,3-Benzenediacetonitrile,
a, a, a', a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl).
Its molecular formula is C17H19N5
Anastrozole is an off-white powder with a molecular weight
of 293.4. Anastrozole has moderate aqueous solubility (0.5
mg/mL at 25°C); solubility is independent of pH in the
physiological range. Anastrozole is freely soluble in methanol,
acetone, ethanol, and tetrahydrofuran, and very soluble
in acetonitrile.
Each tablet contains as inactive ingredients: lactose, magnesium
stearate, hydroxypropylmethylcellulose, polyethylene glycol,
povidone, sodium starch glycolate, and titanium dioxide.
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