DESCRIPTION
Glimepiride tablets are an oral blood-glucose-lowering
drug of the sulfonylurea class. Glimepiride is a white to
yellowish-white, crystalline, odorless to practically odorless
powder formulated into tablets of 1-mg, 2-mg, and 4-mg strengths
for oral administration. Amaryl tablets contain the active
ingredient glimepiride and the following inactive ingredients:
lactose (hydrous), sodium starch glycolate, povidone, microcrystalline
cellulose, and magnesium stearate. In addition, Amaryl 1-mg
tablets contain ferric oxide red, Amaryl 2-mg tablets contain
ferric oxide yellow and FD&C blue #2 aluminum lake,
and Amaryl 4-mg tablets contain FD&C blue #2 aluminum
lake.
Chemically, glimepiride is identified as 1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)
ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea.
The Molecular Formula for Glimepiride is: C24H34N4O5S.
The molecular weight is 490.62.
Glimepiride is practically insoluble
in water.
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