DESCRIPTION

Methyldopa is an antihypertensive drug.

Methyldopa is the L-isomer of alpha-methyldopa. Its chemical name is levo-3-(3,4- dihydroxyphenyl)-2-methylalanine sesquihydrate.

Methyldopa is a white to yellowish white, odorless fine powder, and is sparingly soluble in water. Each tablet, for oral administration, contains 250 mg or 500 mg of methyldopa. Potency is calculated in the anhydrous basis. Inactive ingredients: citric acid, colloidal silicon dioxide, edetate disodium, ethylcellulose, hydroxypropyl methylcellulose, magnesium stearate, methylcellulose, polyethylene glycol, sodium starch glycolate and titanium dioxide. In addition, the 250 mg tablet contains calcium sulfate, hydroxypropyl cellulose, and talc, and the 500 mg tablet contains polysorbate 80.